Sunday, 24 July 2022

Drugs safe in pregnancy & breastfeeding

 Breastfeeding while Pregnant: Is it Safe?

Since the past decade, i works as a community pharmacy in Malaysia, many walk-in customers coming asking for medicines safe in pregnancy and breastfeeding. We have to be very careful in prescribing medicines to these group of patients as most of the medicines are under Category C, D & X where these drugs are not suitable in pregnancy use.

To make it simplify, we as a pharmacist got to refer to The MIMS Pregnancy Safety Index.

 

Definition of risks factors

As defined by US FDA, drugs in categories D, X and some cases C may pose some risks to foetus.

Category A: Controlled studies have not demonstrated a foetal risk. (in other words, VERY SAFE)

Category B: In animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women.

Category C: Studies in animals have revealed adverse effects on foetal.

Category D: There is positive evidence of human foetal risk

Category X: Studies in animals or human beings have demonstrated foetal abnormalities. (In other words, the drug is contraindicated in pregnant women).


Below are the summary of the drugs that are commonly prescribed by pharmacists.

Drug safe in Pregnancy

Drug safe in breastfeeding

Pain relief

Pain Relief

Paracetamol

Paracetamol

 

Ibuprofen

 

Naproxen

 

 

Antimicrobial

Antimicrobial

Amoxicillin (Ospamox)

Fluconazole (Diflucan / Fukole)

 

Miconazole cream (Zarin Cream)

 

Clotrimazole cream (Candazole Cream)

 

Amoxicillin (Ospamox)

 

Cephalexin

 

 

Antihistamine

Antihistamine

Loratadine (Ezede/ Clarirtyn/ Avorious)

Loratadine (Ezede/ Clarirtyn/ Avorious)

Cetirizine (Zyrtec)

Fexofenadine (Telfast/ Fexovid)

 

Cetirizine (Zyrtec)

 

 

 

Birth Control Pills

 

Progestin-only contraceptives (Noriday)

 

 

Gastric medications

Gastric Medications

Alginates (Gaviscon Liq)

Famotidine

Omeprazole (Promesec)

Cimetidine

 

Alginates (Gaviscon Liq)

 

 

 

Antidepressants

 

Paroxetine (Apo-Paroxetine / Seroxat CR)

 

Sertraline (Zoloft)

 

Fluvoxamine (Luvox)

 

 

Constipation

Constipation

Lactulose (Duphalac / Lactul)

Lactulose (Duphalac / Lactul)

 

 

Anti-diarrhoea

Anti-diarrhoea

Loperamide (Lomide)

Loperamide (Lomide)






References: MIMS

 



Disclamer: Please consult your healthcare professionals like doctors, pharmacists for more details.





























































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